International Review of Ophthalmology ›› 2023, Vol. 47 ›› Issue (3): 210-217.doi: 10.3760/ cma.j.issn.1673-5803.2023.03.003

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Research progress on ocular administration methods

Chen Xinyi1,  He Ting2,  Shen Ting3   

  1. 1 Zhejiang University of Technology, Hangzhou 310014,China; 2 Department of Ophthalmology, Zhejiang Provincial People's Hospital, Affiliated People's Hospital, Hangzhou Medical College, Hangzhou 310014, China; 3 Eye Center, the Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310002, China

  • Received:2022-08-09 Online:2023-06-22 Published:2023-06-29
  • Contact: Shen Ting, Email: medicat@zju.edu.cn
  • Supported by:
     National Natural Science Foundaion of China(81700795)

Abstract: In recent years, various new dosage forms of ocular drugs have been developed, such as nano preparations (including nanoparticles, nanospheres, nanoemulsions, nanosuspensions, nanoliposomes, nanomicelles, fluorescent nano and dendritic macromolecules, etc.), sustained-release gels (including temperature-sensitive, pH, ionic and self-assembled peptide hydrogels, etc.), contact lenses, implants, microneedles, etc., which effectively improve the bioavailability of ocular drug administration, patient compliance, and achieve continuous administration, reduce drug side effects, and reduce chronic damage to the eyes , improves the therapeutic effect of eye medication. (Int Rev Ophthalmol, 2023, 47: 210-217)

Key words: nanometre, gel, contact lens, implants, microneedling